Synthesis of 3-(aryl)-2-thioxo-2,3-dihydroquinazolin-4(1 H)-one derivatives using heteropolyacids as green, heterogeneous and recyclable catalysts

Reaction of isatoic anhydride with aniline derivatives gave 2-amino- N-(aryl)benzamides. The latters reacted with phenylisothiocyanate in the presence of heteropolyacids in various solvents which afforded 3-(aryl)-2-thioxo-2,3-dihydroquinazolin-4(1 H)-one derivatives. The effects of various heteropo...

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Bibliographic Details
Published inChinese chemical letters Vol. 22; no. 2; pp. 131 - 134
Main Authors Allameh, S., Heravi, M.M., Hashemi, M.M., Bamoharram, F.F.
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.02.2011
Department of Chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran%Department of Chemistry, School of Sciences, Alzahra University, Vanak,Tehran, Iran%Department of Chemistry, Faculty of Sciences, Islamic Azad University, Mashhad Branch, Mashhad, Iran
Subjects
Heterogeneous
Heteropolyacids
Recyclable catalysts
Thioxo-quinazolinones
Recyclable catalysts
Heteropolyacids
Heterogeneous
Thioxo-quinazolinones
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Summary:Reaction of isatoic anhydride with aniline derivatives gave 2-amino- N-(aryl)benzamides. The latters reacted with phenylisothiocyanate in the presence of heteropolyacids in various solvents which afforded 3-(aryl)-2-thioxo-2,3-dihydroquinazolin-4(1 H)-one derivatives. The effects of various heteropolyacids including Preyssler and Keggin on the yields and reaction times have been investigated.
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2010.10.012