Investigation of trace elements in cancer kidney tissues by SRIXE and PIXE

• Published in: Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms Vol. 109; pp. 284 - 288
• Main Authors: Kwiatek, W.M., Drewniak, T., Lekka, M., Wajdowicz, A.
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 1996
• ISSN: 0168-583X; 1872-9584
• DOI: 10.1016/0168-583X(95)00923-X

In November 1994 we performed some preliminary studies on cancer kidney tissues. The objective of the measurements was to find a difference in trace element concentrations between normal and cancerous kidney tissue. All targets were prepared as pellets of more or less the same weight and thickness. Kidney samples were obtained during surgical operations done in the Clinic of Urology in Cracow. All kidneys were subject to removal due to cancer disease. Samples for analysis were taken from the cancerous part of the kidney and the non-cancerous one. All samples were analyzed by means of SRIXE (Synchrotron Radiation Induced X-ray Emission) at the NSLS (National Synchrotron Light Source) in BNL (Brookhaven National Laboratory) and by means of PIXE at INP (Institute of Nuclear Physics) in Cracow. According to the physician's investigations, cadmium plays a role in oxidation process during tumor growth. Also the other elements i.e. selenium plays here a significant role. The results obtained so far seem to be interesting and may confirm our hypothesis about the cancer process in the kidney, the hypothesis will be a subject of further study. The applied analytical technique enables us to analyze with high precision even a small region of samples.