A Study on the Antioxidant Activity of Pyridylselenium Compounds and their Slow Release from Poly(acrylamide) Hydrogels

The antioxidant activity of pyridylselenium compounds has been evaluated by 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical and nitric oxide (NO) scavenging methods. Pyridylselenium compounds have shown far superior (100-1000 times) antioxidant property than ebselen. The control release of bis(2-p...

Full description

Saved in:
Bibliographic Details
Published inPhosphorus, sulfur, and silicon and the related elements Vol. 189; no. 5; pp. 687 - 699
Main Authors Dhau, Jaspreet S., Singh, Avtar, Singh, Amritpal, Sooch, Balwinder S.
Format Journal Article
LanguageEnglish
Published Abingdon Taylor & Francis 04.05.2014
Taylor & Francis Ltd
Subjects
Antioxidant
Control release
Poly(acrylamide) hydrogels
Pyridylselenium
Online AccessGet full text

Cover

More Information
Summary:The antioxidant activity of pyridylselenium compounds has been evaluated by 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical and nitric oxide (NO) scavenging methods. Pyridylselenium compounds have shown far superior (100-1000 times) antioxidant property than ebselen. The control release of bis(2-pyridyl) diselenide from poly(acrylamide) hydrogels has been studied in order to evaluate its release mechanism and diffusion coefficient. The later study also demonstrates that the pyridylselenium loading into the polymer matrix increases the magnitude and the rate of the radical scavenging activity of the poly(acrylamide) hydrogels.
ISSN:1042-6507
1563-5325
DOI:10.1080/10426507.2013.844143