Exploring the structure–function relationship in a hypothetical membrane protein from a nucleotide sequence

An educational activity is proposed that uses software for proteomic analysis and databases available for free on the Internet to estimate the structure and function of a hypothetical protein from its coding nucleotide sequence. This bioinformatics activity is recommended for integrated introductory...

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Bibliographic Details
Published inBiochemistry and molecular biology education Vol. 49; no. 4; pp. 652 - 657
Main Authors Osorio, Manuel I., Salinas, Dino G.
Format Journal Article
LanguageEnglish
Published Hoboken, USA John Wiley & Sons, Inc 01.07.2021
Wiley
Wiley Subscription Services, Inc
Subjects
Amino acid sequence
Bioinformatics
Biology
Information Science
Introductory Courses
Membrane proteins
Nucleotide sequence
protein structure
Science Activities
Science Instruction
Structure-function relationships
undergraduate
protein structure
undergraduate
bioinformatics
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Summary:An educational activity is proposed that uses software for proteomic analysis and databases available for free on the Internet to estimate the structure and function of a hypothetical protein from its coding nucleotide sequence. This bioinformatics activity is recommended for integrated introductory courses that address the structure function relationship in proteins. Bioinformatic tools are used to deepen the structure/function relationship in proteins, using the glucose transporter Glut1, starting from A coding DNA sequence.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1470-8175
1539-3429
DOI:10.1002/bmb.21524