The use of 5% lidocaine for prolonged analgesia in chronic pain patients: A new technique

• Published in: Regional anesthesia and pain medicine Vol. 23; no. 1; pp. 96 - 100
• Main Authors: Choi, Young K., Liu, Joseph
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 1998
• Subjects: Adult; Aged; Anesthetics, Local - therapeutic use; Chronic Disease; chronic pain; Female; Humans; lidocaine; Lidocaine - therapeutic use; Male; neurolysis; Pain - drug therapy; chronic pain; lidocaine; neurolysis
• ISSN: 1098-7339; 1532-8651
• DOI: 10.1016/S1098-7339(98)90118-3

Background and Objectives. It has been found that 5% lidocaine with 7.5% dextrose causes irreversible conduction block in animal studies. Our case report subjects allowed us to observe the efficacy of 5% lidocaine for a prolonged analgesia in vivo. Method. After performing a diagnostic nerve block with 1% lidocaine, 5% lidocaine with 7.5% dextrose was injected into three patients with trigeminal neuralgia, post-herpetic occipital neuralgia, and intercostal neuralgia, respectively. The patients were followed for one and a half years. Visual Analog Scale (VAS) scores and the side effects were recorded for each patient. Results. One patient received a trigeminal block and one patient received an occipital nerve block. Both patients reported immediate and complete pain relief lasting 14 and 8 months, respectively. One patient, given an intercostal nerve block, received immediate pain relief lasting 5 weeks. None of these patients exhibited any appreciable side effects or complications. Conclusions. Our observations suggest that 5% lidocaine may be used safely and effectively for the purpose of prolonged analgesia in selected patients with intractable chronic pain syndromes.