Anticoagulation properties of virgin coconut oil-loaded electrospun polyurethane/polycaprolactone membrane

•PU/PCL membranes loaded with virgin coconut oil (VCO) were fabricated.•VCO treatment inhibited the adhesion of blood cells and promoted anti-coagulation behavior.•The presence of VCO in membranes supported cell viability. This study aims to produce an electrospun polyurethane/polycaprolactone (PU/P...

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Bibliographic Details
Published inMaterials letters Vol. 320; p. 132403
Main Authors Nguyen, Huy, Nguyen, Nghi, Tran, Nam, Nguyen, Thien, Nguyen, Quang, Phan, Thang, Ta, Hanh, Vo, Toi, Nguyen, Thi-Hiep
Format Journal Article
LanguageEnglish
Published Amsterdam Elsevier B.V 01.08.2022
Elsevier BV
Subjects
Blood cells
Cell adhesion
Coagulation
Coconut oil
Electrospinning
Materials science
Membranes
Polycaprolactone
Polyurethane
Polyurethane resins
Virgin coconut oil
Electrospinning
Virgin coconut oil
Polycaprolactone
Polyurethane
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Summary:•PU/PCL membranes loaded with virgin coconut oil (VCO) were fabricated.•VCO treatment inhibited the adhesion of blood cells and promoted anti-coagulation behavior.•The presence of VCO in membranes supported cell viability. This study aims to produce an electrospun polyurethane/polycaprolactone (PU/PCL) membrane loaded with virgin coconut oil (VCO) for improved antithrombogenicity. The results showed that the addition of VCO plays a remarkable role in mitigating blood cells adhesion, promoting anti-coagulation and aiding cell adhesion.
ISSN:0167-577X
1873-4979
DOI:10.1016/j.matlet.2022.132403