Incorporation of molecularly imprinted polymer nanoparticles in electrospun polycaprolactone fibers

• Published in: Materials letters Vol. 275; p. 128088
• Main Authors: Moraes Segundo, João de Deus Pereira de, Oneide Silva de Moraes, Maria, Brito, Walter Ricardo, d'Ávila, Marcos Akira
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 15.09.2020; Elsevier BV
• Subjects: Biosensors; Chemical synthesis; Electrospinning; Fibers; Imprinted polymers; Incorporation; Materials science; Membranes; Molecular imprinting; Molecularly imprinted polymer; Morphology; Nanoparticles; Polycaprolactone; Tensile properties; Nanoparticles; Electrospinning; Molecularly imprinted polymer
• ISSN: 0167-577X; 1873-4979
• DOI: 10.1016/j.matlet.2020.128088

[Display omitted] •Molecularly imprinted polymer nanoparticles for β-caryophyllene were synthesized.•Electrospinning produced PCL fibers containing the nanoparticles.•Membrane imprinted molecularly for β-caryophyllene was obtained by electrospinning. Polymers synthesized by molecular imprinting technology are commonly known as molecularly imprinted polymers (MIP). In this work, nanoparticles of MIP for β-caryophyllene (NP-MIP-βCP) were synthesized and incorporated into poly (ε-caprolactone) PCL fibers by electrospinning, where morphological characterization was performed by SEM and average diameter of 129 ± 32.3 nm was found. Also, PCL electrospun fiber diameters without and with nanoparticles were 1.66 ± 1.12 and 0.70 ± 0.24 µm, respectively. Chemical characterization by infrared spectroscopy (FTIR) confirmed the synthesis of the NP-MIP-βCP and vibrational band present at 1628 cm−1 indicates the insertion of the NP-MIP-βCP into PCL fibers. It was found the influence of the incorporation of NP-MIP-βCP in thermal and tensile properties of the PCL electrospun membrane. Therefore, NP-MIP-βCP can be incorporated in PCL electrospun membranes by electrospinning and presents a potential application in the pharmaceutical and biomedicine areas, and biosensors.