New sensing mechanisms for design of fluorescent chemosensors emerging in recent years
During the past decade, fluorescent chemosensors have become an important research field of supramolecular chemistry and have attracted great attention because of their simplicity, high selectivity and sensitivity in fluorescent assays. In the design of new fluorescent chemosensors, exploration of n...
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| Published in | Chemical Society reviews Vol. 4; no. 7; pp. 3483 - 3495 |
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| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
01.07.2011
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| Subjects | |
| Online Access | Get full text |
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| Summary: | During the past decade, fluorescent chemosensors have become an important research field of supramolecular chemistry and have attracted great attention because of their simplicity, high selectivity and sensitivity in fluorescent assays. In the design of new fluorescent chemosensors, exploration of new sensing mechanisms between recognition and signal reporting units is of continuing interest. Based on different photophysical processes, conventional sensing mechanisms including photo-induced electron transfer (PET), intramolecular charge transfer (ICT), metal-ligand charge transfer (MLCT), twisted intramolecular charge transfer (TICT), electronic energy transfer (EET), fluorescence resonance energy transfer (FRET), and excimer/exciplex formation have been investigated and reviewed extensively in the literature. This
tutorial review
will mainly focus on new fluorescent sensing mechanisms that have emerged in the past five years, such as aggregation-induced emission (AIE) and C&z.dbd;N isomerization, which can be ascribed to fluorescence changes
via
conformational restriction. In addition, excited-state intramolecular proton transfer (ESIPT) has not been well reviewed yet, although a number of chemosensors based on the ESIPT mechanism have been reported. Thus, ESIPT-based chemosensors have been also summarized in this review.
This tutorial review highlights relatively new fluorescent sensing mechanisms emerging in the past five years, such as aggregation-induced emission (AIE), C&z.dbd;N isomerization, and excited-state intramolecular proton transfer (ESIPT). |
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| Bibliography: | Weimin Liu is a research associate at TIPC. She received her PhD in organic chemistry from TIPC in 2007. Her current research interests mainly focus on the design of chemosensors and luminescent materials. Hongyan Zhang is an associate professor at TIPC. She received her PhD in 2005 from Changchun Institute of Optics and Fine Mechanics and Physics, CAS, and worked as a postdoctoral at Institute of Physics, CAS (2005-2006). She joined TIPC in 2007. Her main research interests include development of optical detection system. Pengfei Wang is a professor at TIPC. He received his PhD in organic chemistry from Institute of Photographic Chemistry, CAS in 1993. After completing professional experience at Laboratoire PPSM of CNRS (France) as a visiting researcher, at the National Institute of Materials and Chemical Research (NIMC), Tsukuba, Japan, as a COE fellow, and at the Department of Applied Physics and Materials Science, City University of Hong Kong as a senior research fellow, he joined TIPC in 2005 as a professor. His current research interests include chemosensors/biosensors, organic opto-electronic materials and devices. Jiechao Ge is currently an associate professor at TIPC. He received his PhD from Shandong Normal University in 2008, and worked as a postdoctoral at Virginia Polytechnic Institute & State University (2008-2009). He joined TIPC in 2010. His main research interests include synthesis of luminescent probes and their applications in biology. Jiasheng Wu received his PhD in 2006 from Technical Institute of Physics and Chemistry, Chinese Academy of Sciences (TIPC, CAS). After working in Korea and Hong Kong as a postdoctoral researcher for nearly three years, he joined Prof. Pengfei Wang's group in 2009. His current research interests include design and synthesis of fluorescent chemosensors/biosenors. ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
| ISSN: | 0306-0012 1460-4744 |
| DOI: | 10.1039/c0cs00224k |