Summary of 32 patients with cardiac syndrome X treated by TCM therapy of regulating qi relieving chest stuffiness and promoting blood circulation

• Published in: Chinese journal of integrative medicine Vol. 13; no. 1; pp. 17 - 21
• Main Authors: Mao, Jing-Yuan, Ge, Yong-Bin, Wang, Heng-He, Wang, Qiang, Zhang, Yun, Yu, Dong-Ling, Zhang, Yu, Huang, Qi, Zhao, Zhi-Qiang, Zhao, Gui-Feng, Wang, Zhan-Wu, Ma, Xue-Peng, Zhang, Zhen-Peng, Li, Ming, Shao, Lei, Zhao, Chun-Yan
• Format: Journal Article
• Language: English
• Published: China Cardiovascular Department,the First Teachina Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300193%Guang'anmen Hospital of China Academy of Chinese Medical Sciences%Tianjin University of Traditional Chinese Medicine 01.03.2007
• Subjects: Blood Circulation; Drug Combinations; Drugs, Chinese Herbal - adverse effects; Drugs, Chinese Herbal - therapeutic use; Exercise Test; Female; Humans; Male; Microvascular Angina - diagnosis; Microvascular Angina - physiopathology; Microvascular Angina - therapy; Middle Aged; Thorax - physiopathology; Treatment Outcome; cardiac syndrome X; qi stagnation; relieving chest stuffiness and promoting blood circulation method; regulating qi; phlegm obstruction and blood stasis
• ISSN: 1672-0415; 1993-0402
• DOI: 10.1007/s11655-007-0017-9

To evaluate the clinical effect of Liqi Kuanxiong Huoxue method LKH, traditional Chinese medicine, TCM therapeutic method for regulating qi, relieving chest stuffiness and promoting blood circulation) in treating patients with cardiac syndrome X (CSX). The prospective, non-randomized controlled study was conducted on 51 selected patients with CSX, who were non-randomly assigned to 2 groups, the treated group treated with LKH in addition to the conventional treatment (32 patients), and the control group treated with conventional treatment (19 patients) like nitrate, diltiazem hydrochloride, etc. The treatment course was 14 days. The changes of such symptoms as angina pectoris, TCM syndrome and indexes of treadmill exercise test before and after treatment were observed. After treatment, such symptoms as chest pain and stuffy feeling and palpitation in the treated group were improved more than those in the control group (P<0.05); the total effective rate on angina pectoris and TCM syndrome in the treated group was better than that in the control group (P<0.05). The treadmill exercise test showed that the maximal metabolic equivalent (Max MET), the time of angina onset and ST segment depression by 0.1 mV were obviously improved after treatment in both groups, but the improvement in the treated group was better than that in the control group respectively (P<0.05). The LKH method could reduce the frequency of angina attacks and improve the clinical condition of patients with CSX.