Novel One-Pot Synthesis for 2,5-Diaryl and 5-Aryl-pyridazin-3(2H)-ones

A novel method for the synthesis of 2-phenyl-5-(o-hydroxyphenyl)-pyridazin-3(2H)-ones and 5-(o-hydroxyphenyl)-pyridazin-3(2H)-ones has been found during the reaction of 4-bromomethylcoumarins with phenylhydrazine and hydrazinehydrate, respectively, under controlled alkaline conditions.

Saved in:
Bibliographic Details
Published inSynthetic communications Vol. 41; no. 17; pp. 2569 - 2582
Main Authors Basanagouda, Mahantesha, Kulkarni, Manohar V.
Format Journal Article
LanguageEnglish
Published PHILADELPHIA Taylor & Francis Group 01.09.2011
Taylor & Francis
Taylor & Francis Ltd
Subjects
Chemistry
Chemistry, Organic
Coumarin
diphenyl
heterocycle
hydrazinehydrate
phenylhydrazine
Physical Sciences
pyridazinone
Science & Technology
diphenyl
phenylhydrazine
COUPLING REACTIONS
SAR
pyridazinone
heterocycle
PYRIDAZINONES
Coumarin
hydrazinehydrate
DERIVATIVES
Online AccessGet full text

Cover

More Information
Summary:A novel method for the synthesis of 2-phenyl-5-(o-hydroxyphenyl)-pyridazin-3(2H)-ones and 5-(o-hydroxyphenyl)-pyridazin-3(2H)-ones has been found during the reaction of 4-bromomethylcoumarins with phenylhydrazine and hydrazinehydrate, respectively, under controlled alkaline conditions.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397911.2010.515330