A facile protocol for the synthesis of 3-aminoimidazo-fused heterocycles via the Groebke-Blackburn-Bienayme reaction under catalyst-free and solvent-free conditions

A one-pot catalyst, solvent, work-up and column free synthesis of 3-aminoimidazo-fused heterocycles by a three-component reaction of a 2-aminoheterocycle, aldehyde, and isocyanide is presented. This efficient and green protocol has the advantages of environmental friendliness, high yields and operat...

Full description

Saved in:
Bibliographic Details
Published inGreen chemistry : an international journal and green chemistry resource : GC Vol. 16; no. 3; pp. 1168 - 1175
Main Authors Vidyacharan, Shinde, Shinde, Anand H., Satpathi, Bishnupada, Sharada, Duddu S.
Format Journal Article
LanguageEnglish
Published CAMBRIDGE Royal Soc Chemistry 01.01.2014
Subjects
Chemistry
Chemistry, Multidisciplinary
Green & Sustainable Science & Technology
Physical Sciences
Science & Technology
Science & Technology - Other Topics
MULTICOMPONENT REACTIONS
ANNULATED PYRIDINES
BENIGN SYNTHESIS
CONSTRUCTION
REGIOSELECTIVE SYNTHESIS
CHEMISTRY
PYRIMIDINES
3-COMPONENT CONDENSATION
INHIBITORS
PYRAZINES
Online AccessGet full text

Cover

More Information
Summary:A one-pot catalyst, solvent, work-up and column free synthesis of 3-aminoimidazo-fused heterocycles by a three-component reaction of a 2-aminoheterocycle, aldehyde, and isocyanide is presented. This efficient and green protocol has the advantages of environmental friendliness, high yields and operational simplicity.
ISSN:1463-9262
1463-9270
DOI:10.1039/c3gc42130a