Food Supplements for Skin Health: In Vitro Efficacy of a Combination of Rhodiola rosea, Tribulus terrestris, Moringa oleifera and Undaria pinnatifida on UV-Induced Damage

An increasing number of people seek treatment for aging-related conditions. Plant-derived nutraceuticals are currently of great interest in the setting of dermo-cosmetic studies for their preventive role in photoaging. We conducted an in vitro study on the possible preventive properties against phot...

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Bibliographic Details
Published inCosmetics (Basel) Vol. 10; no. 3; p. 83
Main Authors Paganelli, Alessia, Pisciotta, Alessandra, Bertani, Giulia, Di Tinco, Rosanna, Tagliaferri, Nadia, Orlandi, Giulia, Azzoni, Paola, Bertoni, Laura
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 01.06.2023
Subjects
Acids
Aging
Dietary supplements
Fibroblasts
Folic acid
Immunofluorescence
Inflammation
Keratinocytes
Moringa
Moringa oleifera
nutraceuticals
oral supplements
Plants
Rhodiola
Rhodiola rosea
Senescence
Skin
skin aging
Tribulus
Tribulus terrestris
Undaria pinnatifida
Vitamin B
Vitamin B12
Vitamin C
United States > US
Italy
Germany
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Summary:An increasing number of people seek treatment for aging-related conditions. Plant-derived nutraceuticals are currently of great interest in the setting of dermo-cosmetic studies for their preventive role in photoaging. We conducted an in vitro study on the possible preventive properties against photoaging of a commercially available product (Venerinase®). A mixture of Rhodiola rosea, Tribulus terrestris, Moringa oleifera, Undaria pinnatifida, folic acid and vitamin B12 (Venerinase®) was tested for its potential anti-aging effects on the skin in vitro. Conventional histology, immunofluorescence and real time PCR were employed in the research protocol. The tested product was proven to prevent UV-induced morphological changes both in keratinocytes and fibroblasts. Moreover, senescence-related and proinflammatory pathways commonly triggered by UV exposure were demonstrated to be inhibited by Venerinase® pretreatment. Our results support the potential clinical benefits of oral supplements for the treatment and/or prevention of cutaneous photodamage.
ISSN:2079-9284
2079-9284
DOI:10.3390/cosmetics10030083