Lymphoma with cutaneous involvement in three domestic rabbits (Oryctolagus cuniculus)

Three domestic rabbits (Oryctolagus cuniculus) with cutaneous lymphoma are described. Two rabbits were young (7 weeks and 1 years) and were euthanized within 1 week of showing clinical signs. Lymphoma was found in the skin and internal organs. The third rabbit was 9.5 years of age, and lived for mor...

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Published inVeterinary dermatology Vol. 11; no. 1; pp. 61 - 67
Main Authors White, S.D, Campbell, T, Logan, A, Meredith, A, Schultheiss, P, Van Winkle, T, Moore, P.F, Naydan, D.K, Mallon, F
Format Journal Article
LanguageEnglish
Published Oxford, UK Blackwell Science Ltd 01.03.2000
Subjects
alpha‐interferon
animal organs
case studies
clinical aspects
cutaneous lymphoma
disease course
lesions
lymphoma
rabbit
rabbits
retinoids
skin
treatment
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Summary:Three domestic rabbits (Oryctolagus cuniculus) with cutaneous lymphoma are described. Two rabbits were young (7 weeks and 1 years) and were euthanized within 1 week of showing clinical signs. Lymphoma was found in the skin and internal organs. The third rabbit was 9.5 years of age, and lived for more than 1 year after diagnosis. No response was seen to either 2 months of alpha‐interferon administration or a 2.5‐week course of isotretinoin treatment. After 1 year the rabbit died suddenly; the owner refused necropsy. Immunologic stains of the tumour in all three rabbits showed T cells to be the lymphoma cell type.
ISSN:0959-4493
1365-3164
DOI:10.1046/j.1365-3164.2000.00159.x