A case report of 2 distinct primary sarcomas arising in an extremity in rapid succession

A 59-year-old male presented with a primary synovial sarcoma around his knee. Two months after resection, he presented with a new, rapidly-growing mass in the ipsilateral proximal thigh. A biopsy of the new mass demonstrated a pleomorphic liposarcoma, distinct from the prior synovial sarcoma. He und...

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Published inRadiology case reports Vol. 18; no. 1; pp. 70 - 74
Main Authors Isaza, Luis F., Garner, Hillary W., Edgar, Mark A., Attia, Steve, Wilke, Benjamin K.
Format Journal Article
LanguageEnglish
Published Elsevier Inc 01.01.2023
Elsevier
Subjects
Case Report
Musculoskeletal oncology
Oncology
Sarcoma
Sarcoma
Musculoskeletal oncology
Oncology
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Summary:A 59-year-old male presented with a primary synovial sarcoma around his knee. Two months after resection, he presented with a new, rapidly-growing mass in the ipsilateral proximal thigh. A biopsy of the new mass demonstrated a pleomorphic liposarcoma, distinct from the prior synovial sarcoma. He underwent neoadjuvant radiation, followed by wide resection. He is now undergoing surveillance for recurrence. While 2 distinct primary sarcomas developing in rapid succession is rare, this case emphasizes the need for a complete work-up, including obtaining a tissue diagnosis for suspected recurrent lesions as this may alter treatment and follow-up recommendations.
ISSN:1930-0433
1930-0433
DOI:10.1016/j.radcr.2022.09.093