Effect of parenteral medications on tcPo2/Pao2 ratios

We studied the effect of parenteral infusions on transcutaneous arterial oxygen tension ratios in 31 newborn rabbits. Tolazoline and prostaglandin E1 produced a significant fall in skin PO2 values (P less than 0.01). Antibiotics, bicarbonate, diazepam, and dopamine infusions produced no change in PO...

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Bibliographic Details
Published inThe Journal of pediatrics Vol. 104; no. 3; pp. 426 - 428
Main Authors PAXSON, C. L. JR, CLAYTON, B. R
Format Journal Article
LanguageEnglish
Published New York, NY Elsevier 01.03.1984
Subjects
Alprostadil
Animals
Animals, Newborn
Biological and medical sciences
Dose-Response Relationship, Drug
Infusions, Parenteral
Medical sciences
Oxygen - blood
Pharmacology. Drug treatments
Prostaglandins E - pharmacology
Rabbits
Skin - blood supply
Skin, nail, hair, dermoskeleton
Tolazoline - pharmacology
Transducers
Drug
PaO2
Vertebrata
Mammalia
Parenteral form
Newborn animal
Interaction
Rabbit
Arterial pressure
Skin
Lagomorpha
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Summary:We studied the effect of parenteral infusions on transcutaneous arterial oxygen tension ratios in 31 newborn rabbits. Tolazoline and prostaglandin E1 produced a significant fall in skin PO2 values (P less than 0.01). Antibiotics, bicarbonate, diazepam, and dopamine infusions produced no change in PO2 ratios.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0022-3476
1097-6833
DOI:10.1016/S0022-3476(84)81110-5