Large Internal Limiting Membrane Tears: Prevalence, Clinical Characteristics, and Surgical Utility

• Published in: American journal of ophthalmology Vol. 245; pp. 115 - 125
• Main Authors: Durrani, Asad F., Hyde, Robert A., Johnson, Mark W.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.01.2023; Elsevier Limited
• Subjects: Asymptomatic; Basement Membrane - pathology; Basement Membrane - surgery; Diplopia; Epiretinal Membrane - diagnosis; Epiretinal Membrane - epidemiology; Epiretinal Membrane - surgery; Humans; Hypotheses; Myopia; Prevalence; Retrospective Studies; Surgeons; Surgery; Tomography, Optical Coherence - methods; Visual Acuity; Vitrectomy - methods
• ISSN: 0002-9394; 1879-1891
• DOI: 10.1016/j.ajo.2022.09.007

To describe the prevalence, clinical and imaging characteristics, and surgical utility of large internal limiting membrane (ILM) tears in eyes with epiretinal membrane (ERM). Retrospective interventional case series. This was a single-institution study including 71 eyes of 70 consecutive patients that underwent ERM peeling by a single vitreoretinal surgeon between 2016 and 2019. Demographic and clinical data were collected from the medical record. ERMs and large ILM tears were identified and analyzed on multimodal imaging. The main outcome measures were the prevalence and characteristics of large ILM tears in eyes undergoing ERM peeling. Large ILM tears were present in 23 of 71 eyes (32.4%) with ERM that underwent surgical management. A review of patients with ERM during the same period who did not undergo surgical management found large ILM tears in 8 of 100 eyes (8.0%). Large ILM tears were commonly associated with other signs of ERM-induced retinal traction, including retinal nerve fiber layer schisis in 20 of 23 eyes (87.0%), inner retinal dimpling in 8 of 23 eyes (34.8%), and discrete paravascular red lesions in 16 of 19 eyes (84.2%). In all eyes stained with brilliant blue G, the preoperative diagnosis of large ILM tear was confirmed and the scrolled ILM edge was used successfully to initiate ILM peeling. Large ILM tears are often present in eyes undergoing surgery for ERM and are likely caused by ERM contracture. Careful preoperative identification of these tears is helpful for surgical planning because the scrolled flap of ILM provides a convenient and safe “handle” for initiating membrane peeling. •Epiretinal membrane (ERM) is a pathologic condition commonly encountered in retina clinics.•Dehiscences of the internal limiting membrane (ILM) can be associated with ERM.•This study characterizes these large ILM tears and their associated findings.•Tangential traction from ERM contracture likely causes ILM tears.•Large ILM tears provide a convenient and safe “handle” to initiate membrane peeling.