Degree-Based Molecular Descriptors and QSPR Analysis of Breast Cancer Drugs

The disease that involves abnormal cell growth and spreads through the surrounding tissues damaging other parts of the body is cancer. Breast cancer is the most common one out of many types. Women are affected by breast cancer either by hormonal changes or genetic changes that occur in DNA. As breas...

Full description

Saved in:
Bibliographic Details
Published inJournal of mathematics (Hidawi) Vol. 2022; no. 1
Main Authors Shanmukha, M. C., Usha, A., Praveen, B. M., Douhadji, Abalo
Format Journal Article
LanguageEnglish
Published Cairo Hindawi 01.01.2022
Hindawi Limited
Wiley
Subjects
Breast cancer
Cancer therapies
Cell division
Chemical compounds
Drugs
Histopathology
Laboratories
Mammography
Mathematics
Molecular structure
Physical properties
Signs and symptoms
Tumors
Online AccessGet full text

Cover

More Information
Summary:The disease that involves abnormal cell growth and spreads through the surrounding tissues damaging other parts of the body is cancer. Breast cancer is the most common one out of many types. Women are affected by breast cancer either by hormonal changes or genetic changes that occur in DNA. As breast cancer is a life-threatening disease, it is necessary for further studies to gear up in fighting the deadliest disease. In this work, a detailed study is made on the occurrence, symptoms, and the drugs involved in its treatment. For this purpose, the quantitative structure-property relationship (QSPR) analysis is made using 21 drugs used in the treatment of breast cancer. The drugs considered in the study are modelled as molecular graphs using their molecular structures, and 11 topological indices are computed. The QSPR analysis is carried out for these drugs, and conclusions are drawn based on the analysis.
ISSN:2314-4629
2314-4785
DOI:10.1155/2022/5880011