Polycaprolactone-templated reduced-graphene oxide liquid crystal nanofibers towards biomedical applications

Here, we report a facile method to generate electrically conductive nanofibers by coating and subsequently chemically reducing graphene oxide (GO) liquid crystals on a polycaprolactone (PCL) mat. Ultra large GO sheets obtained are in favor of charge carrier mobility and oriented morphology of the GO...

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Published inRSC advances Vol. 7; no. 63; pp. 39628 - 39634
Main Authors Jalili-Firoozinezhad, Sasan, Mohamadzadeh Moghadam, Mohamad Hasan, Ghanian, Mohammad Hossein, Ashtiani, Mohammad Kazemi, Alimadadi, Hossein, Baharvand, Hossein, Martin, Ivan, Scherberich, Arnaud
Format Journal Article
LanguageEnglish
Published 2017
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Abstract Here, we report a facile method to generate electrically conductive nanofibers by coating and subsequently chemically reducing graphene oxide (GO) liquid crystals on a polycaprolactone (PCL) mat. Ultra large GO sheets obtained are in favor of charge carrier mobility and oriented morphology of the GO coating. We showed that coating the reduced GO (rGO) not only retains the three-dimensional topography, fiber orientation and size of the template PCL, but also makes it electroconductive. Our preliminary in vitro assessments using mesenchymal stem cells revealed no induced cytotoxicity yet increased cellular metabolism on PCL-templated rGO fibers.
AbstractList Here, we report a facile method to generate electrically conductive nanofibers by coating and subsequently chemically reducing graphene oxide (GO) liquid crystals on a polycaprolactone (PCL) mat. Ultra large GO sheets obtained are in favor of charge carrier mobility and oriented morphology of the GO coating. We showed that coating the reduced GO (rGO) not only retains the three-dimensional topography, fiber orientation and size of the template PCL, but also makes it electroconductive. Our preliminary in vitro assessments using mesenchymal stem cells revealed no induced cytotoxicity yet increased cellular metabolism on PCL-templated rGO fibers.
Author Alimadadi, Hossein
Ghanian, Mohammad Hossein
Jalili-Firoozinezhad, Sasan
Ashtiani, Mohammad Kazemi
Martin, Ivan
Mohamadzadeh Moghadam, Mohamad Hasan
Scherberich, Arnaud
Baharvand, Hossein
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  organization: Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran
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  surname: Scherberich
  fullname: Scherberich, Arnaud
  organization: Department of Biomedicine, University Hospital Basel, University of Basel, CH-4031 Basel, Switzerland
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Snippet Here, we report a facile method to generate electrically conductive nanofibers by coating and subsequently chemically reducing graphene oxide (GO) liquid...
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Title Polycaprolactone-templated reduced-graphene oxide liquid crystal nanofibers towards biomedical applications
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