Polycaprolactone-templated reduced-graphene oxide liquid crystal nanofibers towards biomedical applications

Here, we report a facile method to generate electrically conductive nanofibers by coating and subsequently chemically reducing graphene oxide (GO) liquid crystals on a polycaprolactone (PCL) mat. Ultra large GO sheets obtained are in favor of charge carrier mobility and oriented morphology of the GO...

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Published inRSC advances Vol. 7; no. 63; pp. 39628 - 39634
Main Authors Jalili-Firoozinezhad, Sasan, Mohamadzadeh Moghadam, Mohamad Hasan, Ghanian, Mohammad Hossein, Ashtiani, Mohammad Kazemi, Alimadadi, Hossein, Baharvand, Hossein, Martin, Ivan, Scherberich, Arnaud
Format Journal Article
LanguageEnglish
Published 2017
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Summary:Here, we report a facile method to generate electrically conductive nanofibers by coating and subsequently chemically reducing graphene oxide (GO) liquid crystals on a polycaprolactone (PCL) mat. Ultra large GO sheets obtained are in favor of charge carrier mobility and oriented morphology of the GO coating. We showed that coating the reduced GO (rGO) not only retains the three-dimensional topography, fiber orientation and size of the template PCL, but also makes it electroconductive. Our preliminary in vitro assessments using mesenchymal stem cells revealed no induced cytotoxicity yet increased cellular metabolism on PCL-templated rGO fibers.
ISSN:2046-2069
2046-2069
DOI:10.1039/C7RA06178A