Performance of Non-nasopharyngeal Sample Types for Molecular Detection of SARS-CoV-2

Nasopharyngeal swabs have historically been considered the preferred specimen type for the detection of respiratory viruses, including SARS-CoV-2. However, in response to a global pandemic with shortages of swabs and specimen transport media, limited access to qualified health care personnel, and ne...

Full description

Saved in:
Bibliographic Details
Published inClinics in laboratory medicine Vol. 42; no. 2; p. 249
Main Authors Kukull, Benjamin, Shakir, Salika M, Hanson, Kimberly E
Format Journal Article
LanguageEnglish
Published United States 01.06.2022
Subjects
COVID-19 - diagnosis
COVID-19 Testing
Humans
Molecular Diagnostic Techniques
SARS-CoV-2
COVID-19
Nasopharyngeal swab
Alternative specimen
SARS-CoV-2
Molecular diagnostic
Non-NP respiratory specimen
Online AccessGet more information

Cover

More Information
Summary:Nasopharyngeal swabs have historically been considered the preferred specimen type for the detection of respiratory viruses, including SARS-CoV-2. However, in response to a global pandemic with shortages of swabs and specimen transport media, limited access to qualified health care personnel, and needs for large-scale testing in nonmedical settings, alternative sample types have been validated for COVID-19 diagnosis. The purpose of this review is to highlight the diagnostic accuracy and clinical utility of non-nasopharyngeal respiratory samples for SARS-CoV-2 molecular diagnostic testing.
ISSN:1557-9832
DOI:10.1016/j.cll.2022.02.002