Acquired Immunologic Neuropathies

The acquired immunologic neuropathies are a collection of neuropathic conditions that result from abnormal immune responses that target peripheral nerve myelin, Schwann cells, or axons. Although the clinical features and diagnostic data are sometimes overlapping, the specific disorders are heterogen...

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Bibliographic Details
Published inSeminars in neurology Vol. 35; no. 4; p. 398
Main Authors Allen, Jeffrey A, Parry, Gareth J
Format Journal Article
LanguageEnglish
Published United States 01.08.2015
Subjects
Humans
Immune System Diseases - complications
Immune System Diseases - diagnosis
Immune System Diseases - therapy
Neuropathology
Peripheral Nervous System Diseases - complications
Peripheral Nervous System Diseases - diagnosis
Peripheral Nervous System Diseases - therapy
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Summary:The acquired immunologic neuropathies are a collection of neuropathic conditions that result from abnormal immune responses that target peripheral nerve myelin, Schwann cells, or axons. Although the clinical features and diagnostic data are sometimes overlapping, the specific disorders are heterogeneous in pathogenesis, treatment, and prognosis. Importantly, there is no consensus as to which neuropathies are distinct conditions and which are better considered as variants or subtypes. The authors discuss the clinical, electrophysiological, histopathological, and treatment features that define the acquired immunomediated neuropathies, calling attention to differences that are observed between the specific neuropathies as well as the differences in the presumed variants within each syndrome.
ISSN:1098-9021
DOI:10.1055/s-0035-1558974