Ergot and Its Alkaloids

This manuscript reviews the history and pharmacognosy of ergot, and describes the isolation/preparation, chemistry, pharmacodynamics, and pharmacotherapeutics of the major ergot alkaloids and their derivatives. A brief discussion of the hallucinogenic properties of lysergic acid diethylamide is also...

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Bibliographic Details
Published inAmerican journal of pharmaceutical education Vol. 70; no. 5; p. 98
Main Author Schiff, Paul L.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 15.10.2006
American Journal of Pharmaceutical Education
Subjects
Animals
Ergot Alkaloids - chemistry
Ergot Alkaloids - isolation & purification
Ergot Alkaloids - metabolism
Ergot Alkaloids - pharmacology
Hallucinogens - chemistry
Hallucinogens - isolation & purification
Hallucinogens - metabolism
Hallucinogens - pharmacology
Humans
Lysergic Acid Diethylamide - chemistry
Lysergic Acid Diethylamide - isolation & purification
Lysergic Acid Diethylamide - metabolism
Lysergic Acid Diethylamide - pharmacology
Receptors, Serotonin - metabolism
Teachers' Topics
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Summary:This manuscript reviews the history and pharmacognosy of ergot, and describes the isolation/preparation, chemistry, pharmacodynamics, and pharmacotherapeutics of the major ergot alkaloids and their derivatives. A brief discussion of the hallucinogenic properties of lysergic acid diethylamide is also featured. An abbreviated form of the material found in this paper is presented in a 4-hour didactic format to third-professional year PharmD students as part of their study of vascular migraine headaches, Parkinson's disease, and naturally occurring hallucinogens/hallucinogen derivatives in the modular course offering Neurology/Psychiatry.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0002-9459
1553-6467
DOI:10.1016/S0002-9459(24)07817-3