Urinary Detection of Hydroxycinnamates and Flavonoids in Humans after High Dietary Intake of Fruit

The determination of the abilities of flavonoids, hydroxycinnamates and phenolics to scavenge free radicals in vitro suggests potent combined antioxidant activities of fruits, vegetables, beverages and grains. However, the key question of uptake in humans has only recently been approached consistent...

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Bibliographic Details
Published inFree radical research Vol. 28; no. 4; pp. 429 - 438
Main Authors Bourne, Louise C., Rice-Evans, Catherine A.
Format Journal Article
LanguageEnglish
Published England Informa UK Ltd 01.01.1998
Taylor & Francis
Subjects
absorption
Adult
caffeic acid
Caffeic Acids - pharmacokinetics
Caffeic Acids - urine
Chromatography, High Pressure Liquid - methods
Coumaric Acids - pharmacokinetics
Coumaric Acids - urine
Diet
Female
Ferulic acid
flavonoid
Flavonoids - pharmacokinetics
Flavonoids - urine
Fruit
Humans
hydroxycinnamate
Lycopersicon esculentum
Male
Phenols - pharmacokinetics
Phenols - urine
urinary detection
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Summary:The determination of the abilities of flavonoids, hydroxycinnamates and phenolics to scavenge free radicals in vitro suggests potent combined antioxidant activities of fruits, vegetables, beverages and grains. However, the key question of uptake in humans has only recently been approached consistently. The study described here demonstrates the uptake of hydroxycinnamates, for the first time, and other phenolic components, applying an HPLC method for their detection in the urine of subjects consuming levels of specific fruit equivalent to an approximate intake of 25 mg flavonol glycosides.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:1071-5762
1029-2470
DOI:10.3109/10715769809070812