The liquid-membrane phenomenon in steroidal drugs

The liquid-membrane phenomenon in steroidal drugs has been studied. The drugs and their mixtures with lecithin have been shown to generate a liquid membrane in series with a supporting membrane. The transport of glucose and a few amino acids through the liquid membranes thus generated was also studi...

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Bibliographic Details
Published inColloids and surfaces Vol. 14; no. 1; pp. 1 - 10
Main Authors Srivastava, R.C., Sharma, R.K., Bhise, S.B.
Format Journal Article
LanguageEnglish
Published Amsterdam Elsevier B.V 1985
Elsevier
Subjects
Applied sciences
Exact sciences and technology
Other techniques and industries
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Summary:The liquid-membrane phenomenon in steroidal drugs has been studied. The drugs and their mixtures with lecithin have been shown to generate a liquid membrane in series with a supporting membrane. The transport of glucose and a few amino acids through the liquid membranes thus generated was also studied. The data indicate that the liquid mermbranes generated by the steroidal drugs may play a role in the mechanism of action of the drugs. Three representative steroidal drugs, namely testosterone propionate, ethinylestradiol and hydrocortisone acetate, were chosen for the present study.
ISSN:0166-6622
1873-4340
DOI:10.1016/0166-6622(85)80036-6