The liquid-membrane phenomenon in steroidal drugs
The liquid-membrane phenomenon in steroidal drugs has been studied. The drugs and their mixtures with lecithin have been shown to generate a liquid membrane in series with a supporting membrane. The transport of glucose and a few amino acids through the liquid membranes thus generated was also studi...
Saved in:
Published in | Colloids and surfaces Vol. 14; no. 1; pp. 1 - 10 |
---|---|
Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
Amsterdam
Elsevier B.V
1985
Elsevier |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The liquid-membrane phenomenon in steroidal drugs has been studied. The drugs and their mixtures with lecithin have been shown to generate a liquid membrane in series with a supporting membrane. The transport of glucose and a few amino acids through the liquid membranes thus generated was also studied. The data indicate that the liquid mermbranes generated by the steroidal drugs may play a role in the mechanism of action of the drugs.
Three representative steroidal drugs, namely testosterone propionate, ethinylestradiol and hydrocortisone acetate, were chosen for the present study. |
---|---|
ISSN: | 0166-6622 1873-4340 |
DOI: | 10.1016/0166-6622(85)80036-6 |