Multi-Active Method (MAM) for the Analysis of Agriculture Product Technical Ingredients and Formulated Products

In regulatory laboratories, where potentially hundreds of different types of sample and active ingredients can be evaluated every year, a unique set of conditions provided by agricultural product manufacturers in their regulatory methods are faced with the decision to purchase a new and different an...

Full description

Saved in:
Bibliographic Details
Published inLC GC North America Vol. 41; no. 11; pp. 472 - 478
Main Authors Garvey, Jim, Novakova, Olga, Pigeon, Olivier, McNally, Mary Ellen
Format Magazine Article
LanguageEnglish
Published Monmouth Junction Intellisphere, LLC 01.12.2023
MultiMedia Healthcare Inc
Subjects
Acetone
Acetonitrile
Agriculture
Chromatography
Data systems
Decision analysis
Enforcement
Equivalence
Ethyl acetate
Formic acid
Grinding mills
High performance liquid chromatography
Ingredients
Integrators
Laboratories
Liquid chromatography
Manufacturers
Manufacturing
Mathematical analysis
Methods
Phosphoric acid
Photodiodes
Phthalates
Quality control
Sensors
Ultraviolet detectors
Uniqueness
Water baths
Belgium
Czech Republic
Online AccessGet full text

Cover

More Information
Summary:In regulatory laboratories, where potentially hundreds of different types of sample and active ingredients can be evaluated every year, a unique set of conditions provided by agricultural product manufacturers in their regulatory methods are faced with the decision to purchase a new and different analytical column or not follow the enforcement method provided by the manufacturer. Because of this, a multi-analyte method has been developed at the Irish Department of Agriculture, Food and The Marine, contributed to by the regulatory laboratories in Belgium and the Czech Republic, analyzing more than 70 active ingredients using high performance liquid chromatography (HPLC) and more than 35 active ingredients by ultrahigh-pressure liquid chromatography (UHPLC). The method has been designed for use by quality control laboratories and is suitable for determining a range of active substances in a wider range of formulated products as well as the technical AI itself. The method has been validated for linearity, precision, accuracy, and specificity for seven technical active ingredients as defined by FMC Corporation. The method and results are described in this article.
ISSN:1527-5949
1939-1889
DOI:10.56530/lcgc.na.ei8970k2