Study of Allergic Fungal Sinusitis in 40 Surgical Cases of Chronic Paranasal Sinusitis

• Published in: Nippon Jibi Inkoka Gakkai Kaiho Vol. 105; no. 12; pp. 1198 - 1204
• Main Authors: Kawabori, Shinichi, Watanabe, Akihito, Osanai, Hiroshi, Yoshizaki, Tormoki, Taniguchi, Masanobu
• Format: Journal Article
• Language: English; Japanese
• Published: Japan The Oto-Rhino-Laryngological Society of Japan, Inc 01.12.2002
• Subjects: Adult; Aged; allergic fungal sinusitis; culture; eosinophil; Female; fungus; Humans; Hypersensitivity - complications; IgE; Male; Middle Aged; Mycoses - complications; Sinusitis - complications; Sinusitis - immunology; Sinusitis - surgery
• ISSN: 0030-6622; 1883-0854
• DOI: 10.3950/jibiinkoka.105.1198

Allergic fungal sinusitis is chronic and paranasal, related to fungal allergy. Many papers on allergic fungal sinusitis have been reported in the United State, and the incidence is 5% to 10% among patients with chronic paranasal sinusitis. Although cases of allergic fungal sinusitis have been reported in Japan, the incidence is unclear. We studied allergic fungal sinusitis in 40 consecutive patients-26 men and 14 women-undergoing endoscopic sinus surgery at Keiyukai Sapporo Hospital December 2000 to July 2001. We checked for allergic rhinitis and asthma, a history of surgery for nasal polyps and chronic sinusitis, the presence of nasal polyps, grading of sinusitis via computed tomography, nonspecific IgE and allergen-specific IgE for fungi in serum, eosinophilia in nasal smears, paranasal eosinophilic mucin, and histology and fungal culture of paranasal sinus mucus. None had typical allergic fungal sinusitis, but 1 had eosinophilic paranasal mucin, high IgE, and false-positive IgE for fungi. We studied clinical data and histology of fungi and paranasal mucosa in 9 cases with fungal maxillary sinusitis, but none had allergy or eosinophilc mucin. This suggested that few patients with allergic fungal sinusitis exist among those with chronic paranasal sinusitis.