Synthesis and properties of a fluorescent nucleotide derivative

Strong fluorescent deoxyadenosine derivatives are of considerable research importance in cell biology. We prepared the deoxyriboside of methyl 3,7-dihydro-7-oxo-[2,1-i]pyrimidopurine-9-carboxylate (compound 1b, deoxyribofuranosyl A*)(1) which was subsequently used in the synthesis of the dimer d(A*T...

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Published inRECUEIL DES TRAVAUX CHIMIQUES DES PAYS-BAS-JOURNAL OF THE ROYAL NETHERLANDS CHEMICAL SOCIETY Vol. 115; no. 1; pp. 99 - 103
Main Authors Petra, DGI, deBoer, RF, Koomen, GJ, Meeuwenoord, NJ, KuylYeheskiely, E, vanderMarel, GA, vanBoom, JH
Format Journal Article
LanguageEnglish
Published AMSTERDAM Elsevier 01.01.1996
Subjects
Chemistry
Chemistry, Multidisciplinary
Physical Sciences
Science & Technology
nucleoside analogues
fluorescence
dinucleotide
PYRIDO<2,1-I>PURINES
DNA
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Summary:Strong fluorescent deoxyadenosine derivatives are of considerable research importance in cell biology. We prepared the deoxyriboside of methyl 3,7-dihydro-7-oxo-[2,1-i]pyrimidopurine-9-carboxylate (compound 1b, deoxyribofuranosyl A*)(1) which was subsequently used in the synthesis of the dimer d(A*T).
ISSN:0165-0513
DOI:10.1002/recl.19961150117