Follow-up studies on children with severe dietary chloride deficiency during infancy

• Published in: Pediatrics (Evanston) Vol. 75; no. 1; p. 1
• Main Authors: Hellerstein, S, Duggan, E, Merveille, O, Scarth, L
• Format: Journal Article
• Language: English
• Published: United States 01.01.1985
• Subjects: Alkalosis - etiology; Alkalosis - metabolism; Alkalosis - physiopathology; CARENCE MINERALE; Child Development; Chlorides; CHLORURE; CLORUROS; COMPORTAMIENTO; COMPORTEMENT; DEFICIENCIA DE MINERALES; Deficiency Diseases - etiology; Deficiency Diseases - metabolism; Deficiency Diseases - physiopathology; DIETA; ENFANT; ENFERMEDADES (TRACTO URINARIO); Failure to Thrive - etiology; Failure to Thrive - metabolism; Failure to Thrive - physiopathology; Growth; Hematuria - urine; HIPERCALCEMIA; Humans; HYPERCALCEMIE; Hypokalemia - etiology; Hypokalemia - metabolism; Hypokalemia - physiopathology; Infant; Infant Food - adverse effects; INFANTES; Kidney - physiopathology; MALADIE DE L'APPAREIL URINAIRE; NINOS; NOUVEAU-NE; NUTRICION; NUTRITION; REGIME ALIMENTAIRE; Syndrome
• ISSN: 0031-4005; 1098-4275
• DOI: 10.1542/peds.75.1.1

Extract: Ten children who had severe dietary chloride deficiency during early infancy have grown normally during their first 4 to 5 years. With the exception of 1 child who did not get into the sitting position alone until he was 9-1/2 months of age, the patients reached the usual developmental milestones of the first 2 years during the expected age intervals. Developmental and psychological testing indicates that all of the children have at least average ability. However, 3 children have shown behavior patterns that may interfere with successful school performance. Serum creatinine and urea nitrogen concentrations appear to be normal as does renal concentrating capacity. During a 4-year follow-up, 1 child has shown persistent and a second intermittent microscopic hematuria. (author)