Endodermal sinus tumor (yolk-sac carcinoma) of the orbit

A 15-month-old boy with rapidly progressive proptosis had an unusual malignant germ-cell tumor of the orbit and nasopharynx identified as an endodermal sinus tumor (yolk-sac carcinoma). Endodermal sinus tumors arising in extra gonadal locations are highly malignant and generally lethal. The boy was...

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Bibliographic Details
Published inJournal of pediatric ophthalmology and strabismus Vol. 19; no. 5; pp. 270 - 274
Main Authors Katz, N N, Ruymann, F B, Margo, C E, Popejoy, L A, LaPiana, F G
Format Journal Article
LanguageEnglish
Published United States SLACK INCORPORATED 01.09.1982
Subjects
Exophthalmos - etiology
Humans
Infant
Male
Mesonephroma - pathology
Mesonephroma - therapy
Nasopharyngeal Neoplasms - pathology
Nasopharyngeal Neoplasms - therapy
Neoplasms, Multiple Primary - pathology
Orbital Neoplasms - pathology
Orbital Neoplasms - therapy
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Summary:A 15-month-old boy with rapidly progressive proptosis had an unusual malignant germ-cell tumor of the orbit and nasopharynx identified as an endodermal sinus tumor (yolk-sac carcinoma). Endodermal sinus tumors arising in extra gonadal locations are highly malignant and generally lethal. The boy was treated with radiation and three-drug chemotherapy and has survived more than eight years.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
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ISSN:0191-3913
1938-2405
DOI:10.3928/0191-3913-19820901-20