Alterations of the thalamo-cortical system in rats prenatally exposed to ethanol are prevented by concurrent administration of acetyl- l-carnitine
We previously demonstrated that adult rats prenatally exposed to ethanol display permanent damages of thalamo-cortical connections [18,19,33]. Here the effect of simultaneous administration of ethanol and acetyl- l-carnitine has been investigated. Adult animals underwent cortical or thalamic injecti...
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Published in | Brain research Vol. 698; no. 1; pp. 241 - 247 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
London
Elsevier B.V
06.11.1995
Amsterdam Elsevier New York, NY |
Subjects | |
Online Access | Get full text |
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Summary: | We previously demonstrated that adult rats prenatally exposed to ethanol display permanent damages of thalamo-cortical connections [18,19,33]. Here the effect of simultaneous administration of ethanol and acetyl-
l-carnitine has been investigated. Adult animals underwent cortical or thalamic injections of horseradish peroxidase and both antegrade and retrograde thalamic and cortical labeling have been analyzed. Ethanol-induced changes of thalamo-cortical circuits are prevented by concurrent administration of acetyl-
l-carnitine. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 |
ISSN: | 0006-8993 1872-6240 |
DOI: | 10.1016/0006-8993(95)00997-5 |