Deconvolution based attenuation correction for time-of-flight positron emission tomography

For an accurate quantitative reconstruction of the radioactive tracer distribution in positron emission tomography (PET), we need to take into account the attenuation of the photons by the tissues. For this purpose, we propose an attenuation correction method for the case when a direct measurement o...

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Bibliographic Details
Published inJournal of the Korean Physical Society Vol. 71; no. 7; pp. 426 - 437
Main Author Lee, Nam-Yong
Format Journal Article
LanguageEnglish
Published Seoul The Korean Physical Society 01.10.2017
Springer Nature B.V
한국물리학회
Subjects
Attenuation
Deconvolution
Image reconstruction
Mathematical and Computational Physics
Noise levels
Particle and Nuclear Physics
Photons
Physics
Physics and Astronomy
Positron emission
Theoretical
Tomography
물리학
Wavelets
Wiener filtering
87.57.nf
Attenuation correction
Time-of-flight
PET
87.57.uk
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Summary:For an accurate quantitative reconstruction of the radioactive tracer distribution in positron emission tomography (PET), we need to take into account the attenuation of the photons by the tissues. For this purpose, we propose an attenuation correction method for the case when a direct measurement of the attenuation distribution in the tissues is not available. The proposed method can determine the attenuation factor up to a constant multiple by exploiting the consistency condition that the exact deconvolution of noise-free time-of-flight (TOF) sinogram must satisfy. Simulation studies shows that the proposed method corrects attenuation artifacts quite accurately for TOF sinograms of a wide range of temporal resolutions and noise levels, and improves the image reconstruction for TOF sinograms of higher temporal resolutions by providing more accurate attenuation correction.
ISSN:0374-4884
1976-8524
DOI:10.3938/jkps.71.426