18F-FDG PET/CT in Detecting Metastatic Infection in Children

Metastatic infection is a severe complication of bacteremia with high morbidity and mortality. The aim of this study was to investigate the diagnostic value of 18F-FDG PET combined with CT (FDG PET/CT) in children suspected of having metastatic infection. The results of FDG PET/CT scans performed in...

Full description

Saved in:
Bibliographic Details
Published inClinical nuclear medicine Vol. 41; no. 4; p. 278
Main Authors Kouijzer, Ilse J E, Blokhuis, Gijsbert J, Draaisma, Jos M T, Oyen, Wim J G, de Geus-Oei, Lioe-Fee, Bleeker-Rovers, Chantal P
Format Journal Article
LanguageEnglish
Published United States 01.04.2016
Subjects
Adolescent
Bacteremia - diagnostic imaging
Child
Female
Fluorodeoxyglucose F18
Humans
Infant
Male
Multimodal Imaging
Positron-Emission Tomography
Radiopharmaceuticals
Tomography, X-Ray Computed
Online AccessGet more information

Cover

More Information
Summary:Metastatic infection is a severe complication of bacteremia with high morbidity and mortality. The aim of this study was to investigate the diagnostic value of 18F-FDG PET combined with CT (FDG PET/CT) in children suspected of having metastatic infection. The results of FDG PET/CT scans performed in children because of suspected metastatic infection from September 2003 to June 2013 were analyzed retrospectively. The results were compared with the final clinical diagnosis. FDG PET/CT was performed in 13 children with suspected metastatic infection. Of the total number of FDG PET/CT scans, 38% were clinically helpful. Positive predictive value of FDG PET/CT was 71%, and negative predictive value was 100%. FDG PET/CT appears to be a valuable diagnostic technique in children with suspected metastatic infection. Prospective studies of FDG PET/CT as part of a structured diagnostic protocol are needed to assess the exact additional diagnostic value.
ISSN:1536-0229
DOI:10.1097/RLU.0000000000001119