The biomedical properties of polyethylene terephthalate surface modified by silver ion implantation

• Published in: Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms Vol. 257; no. 1-2; pp. 141 - 145
• Main Authors: Wang, Jin, Li, Jianxin, Shen, Liru, Ling, Ren, Xu, Zejin, Zhao, Ansha, Leng, Yongxiang, Huang, Nan
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.04.2007
• Subjects: Bacterial adhesion; Cell toxicity; Ion implantation; Polyethylene terephthalate (PET); Silver; Staphylococcus epidermidis; Thromboembolic property; 81.05.Lg; Silver; Ion implantation; 87.68.+z; Polyethylene terephthalate (PET); Cell toxicity; Bacterial adhesion; Thromboembolic property
• ISSN: 0168-583X; 1872-9584
• DOI: 10.1016/j.nimb.2006.12.137

Polyethylene terephthalate (PET) film is modified by Ag ion implantation with a fluence 1×1016ions/cm2. The results of X-Ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS) indicate that silver has been successfully implanted into the surface of PET. The PET samples modified by silver ion implantation have significantly bactericidal property. The capacity of the staphylococcus epidermidis (SE) adhered on the Ag+ implanted PET surface is 5.3×106CFU/ml, but the capacity of the SE adhered on the untreated PET film is 2.23×107CFU/ml. The thromboembolic property is evaluated by in vitro platelet adhesion test, and there is not statistically difference between the untreated PET and the Ag+ implanted PET for the number of adhered and activated platelets. The PET implanted by silver ion has not acute toxicity to endothelial cell (EC) which was evaluated by the release of lactate dehydrogenase (LDH) test.