Genomic selection and genetic architecture of agronomic traits during modern rapeseed breeding

• Published in: Nature genetics Vol. 54; no. 5; pp. 694 - 704
• Main Authors: Hu, Jihong, Chen, Biyun, Zhao, Jing, Zhang, Fugui, Xie, Ting, Xu, Kun, Gao, Guizhen, Yan, Guixin, Li, Hongge, Li, Lixia, Ji, Gaoxiang, An, Hong, Li, Hao, Huang, Qian, Zhang, Meili, Wu, Jinfeng, Song, Weilin, Zhang, Xiaojun, Luo, Yujie, Chris Pires, J, Batley, Jacqueline, Tian, Shilin, Wu, Xiaoming
• Format: Journal Article
• Language: English
• Published: United States Nature Publishing Group 01.05.2022
• Subjects: Acids; Adaptation; Agronomy; Brassica; Brassica napus; Brassica napus - genetics; Brassica rapa - genetics; Breeding; Gene frequency; Genes; Genome, Plant - genetics; Genome-wide association studies; Genome-Wide Association Study; Genomes; Genomics; Mutation; Oilseeds; Plant Breeding; Polymorphism, Single Nucleotide - genetics; Rape plants; Rapeseed; Seeds; China
• ISSN: 1061-4036; 1546-1718
• DOI: 10.1038/s41588-022-01055-6

Rapeseed (Brassica napus L.) is an important oil-producing crop for the world. Its adaptation, yield and quality have been considerably improved in recent decades, but the genomic basis underlying successful breeding selection remains unclear. Hence, we conducted a comprehensive genomic assessment of rapeseed in the breeding process based on the whole-genome resequencing of 418 diverse rapeseed accessions. We unraveled the genomic basis for the selection of adaptation and agronomic traits. Genome-wide association studies identified 628 associated loci-related causative candidate genes for 56 agronomically important traits, including plant architecture and yield traits. Furthermore, we uncovered nonsynonymous mutations in plausible candidate genes for agronomic traits with significant differences in allele frequency distributions across the improvement process, including the ribosome recycling factor (BnRRF) gene for seed weight. This study provides insights into the genomic basis for improving rapeseed varieties and a valuable genomic resource for genome-assisted rapeseed breeding.