4-hydroxy- N-methylproline analogues in Melaleuca spp

• Published in: Phytochemistry (Oxford) Vol. 26; no. 12; pp. 3343 - 3344
• Main Authors: Jones, G.P, Naidu, B.P, Paleg, L.G, Tiekink, E.R.T, Snow, M.R
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 1987
• Subjects: (−)-(2 S, 4 R)-1,1′-dimethyl-4-hydroxypyrrolidine-2-carboxylic acid; (−)-(2 S, 4 R)-1-methyl-4-hydroxy-pyrrolidine-2-carboxylic acid; 4-hydroxy- N,N′- dimethylproline; 4-hydroxy- N-methylproline; analogs; betonicine; chemical analysis; chemical constituents of plants; leaves; Melaleuca; melaleuca lanceolata; melaleuca uncinata; Myrtaceae; betonicine; 4-hydroxy- N-methylproline; 4-hydroxy- N,N′- dimethylproline; Myrtaceae; (−)-(2 S, 4 R)-1,1′-dimethyl-4-hydroxypyrrolidine-2-carboxylic acid; Melaleuca; (−)-(2 S, 4 R)-1-methyl-4-hydroxy-pyrrolidine-2-carboxylic acid
• ISSN: 0031-9422; 1873-3700
• DOI: 10.1016/S0031-9422(00)82501-7

4-hydroxy- N-methylproline and 4-hydroxy- N,N′-dimethylproline have been identified in the aqueous extracts of Melaleuca spp. Characterization of the two compounds is discussed.