Chemical constituents, antioxidant, and anticancer activities of bee pollen from various floral sources in Taiwan

Bee pollen has been traditionally used for health promotion. However, the chemical constituents and pharmaceutical effects of bee pollen strongly depend on their sources. This study determined chemical compositions and evaluated the antioxidant and anticancer activity of six bee pollen samples from...

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Published inNotulae botanicae Horti agrobotanici Cluj-Napoca Vol. 50; no. 2; p. 12644
Main Authors NGUYEN, Hoang Chinh, LIU, Liang-Chih, WU, Ming-Cheng, LIN, Tai-Pei, YANG, Chiou-Ying, HUANG, Meng-Yuan
Format Journal Article
LanguageEnglish
Published Cluj-Napoca Notulae Botanicae Horti Agrobotanici Cluj-Napoca 01.01.2022
AcademicPres
Subjects
Anthocyanins
anticancer
Anticancer properties
Antineoplastic drugs
antioxidant
Antioxidants
Antitumor activity
Bee bread
bee pollen
Bees
Bioactive compounds
Biological activity
Cancer
Carotenoids
Cell viability
Chelation
Chemical composition
chemical constituents
Chlorophyll
Chlorophylls
Constituents
Flavonoids
Health promotion
Phenolic compounds
Phenols
Pollen
Scavenging
Tumor cell lines
Taiwan
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Summary:Bee pollen has been traditionally used for health promotion. However, the chemical constituents and pharmaceutical effects of bee pollen strongly depend on their sources. This study determined chemical compositions and evaluated the antioxidant and anticancer activity of six bee pollen samples from Taiwan. The Cs sample contained the highest amounts of carotenoid (417.67 mg/g DW) and anthocyanin (10.96 μmol/g DW) while the Nn sample showed the highest content of chlorophyll (Chl) a (23.39 mg/g DW) and Chl b (39.17 mg/g DW). The highest flavonoid (11.69 mg QE/g DW) and phenolic content (42.91 mg GAE/g DW) were found in Bp and Pm samples, respectively. The highest Fe2+-chelating ability was observed in Bp (IC50 value of 6.28 mg/mL), while Bn exhibited the most effective in scavenging DPPH radical with IC50 value of 3.96 mg/mL. The Bp sample also showed the highest activity against three breast cancer cell lines, MCF-7 (cell viability of 43.5%), BT-20 (cell viability of 0%), and Hs 578T (cell viability of 0%). This study suggested that the level of bioactive compounds and biological activity of bee pollen significantly differ among their sources and the Bp is a potent antioxidant and anticancer agent for medicinal use.
ISSN:0255-965X
1842-4309
DOI:10.15835/nbha50212644