SWI enhances vein detection using gadolinium in multiple sclerosis

Susceptibility weighted imaging (SWI) combined with the FLAIR sequence provides the ability to depict in vivo the perivenous location of inflammatory demyelinating lesions – one of the most specific pathologic features of multiple sclerosis (MS). In addition, in MS white matter (WM) lesions, gadolin...

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Bibliographic Details
Published inActa radiologica open Vol. 4; no. 3; p. 2047981614560938
Main Authors Maggi, Pietro, Mazzoni, Lorenzo N, Moretti, Marco, Grammatico, Matteo, Chiti, Stefano, Massacesi, Luca
Format Journal Article
LanguageEnglish
Published London, England SAGE Publications 01.03.2015
Subjects
Case Report
magnetic resonance imaging (MRI)
inflammation
Central nervous system (CNS)
brain/brain stem
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Summary:Susceptibility weighted imaging (SWI) combined with the FLAIR sequence provides the ability to depict in vivo the perivenous location of inflammatory demyelinating lesions – one of the most specific pathologic features of multiple sclerosis (MS). In addition, in MS white matter (WM) lesions, gadolinium-based contrast media (CM) can increase vein signal loss on SWI. This report focuses on two cases of WM inflammatory lesions enhancing on SWI images after CM injection. In these lesions in fact the CM increased the contrast between the parenchyma and the central vein allowing as well, in one of the two cases, the detection of a vein not visible on the same SWI sequence acquired before CM injection.
ISSN:2058-4601
2058-4601
DOI:10.1177/2047981614560938