Short and efficient preparations of isoxazole-3-carboxylic acid and imino-oxopentanoic acid potent precursors of 4-hydroxyisoleucine

Herein, we describe short and efficient syntheses of isoxazole-3-carboxylic acid 3a and imino-oxopentanoic acid 8 achiral precursors of 4-hydroxyisoleucine. The developed procedures involve readily available and cheap starting materials and can easily be transposed to the large scale. Graphical Abst...

Full description

Saved in:
Bibliographic Details
Published inTetrahedron Vol. 62; no. 18; pp. 4430 - 4434
Main Authors Becht, Jean-Michel, Marin, Sandra De Lamo, Maruani, Martine, Wagner, Alain, Mioskowski, Charles
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 01.05.2006
Elsevier
Subjects
Achiral precursors
Chemistry
Chemistry, Organic
Organic phase
Physical Sciences
Science & Technology
Stereoselective
Organic phase
Achiral precursors
Stereoselective
stereoselective
organic phase
achiral precursors
Online AccessGet full text

Cover

More Information
Summary:Herein, we describe short and efficient syntheses of isoxazole-3-carboxylic acid 3a and imino-oxopentanoic acid 8 achiral precursors of 4-hydroxyisoleucine. The developed procedures involve readily available and cheap starting materials and can easily be transposed to the large scale. Graphical Abstract
ISSN:0040-4020
1464-5416
DOI:10.1016/j.tet.2006.02.056