Mycobacterium avium Complex and Bronchiectasis. There's Something Happening Here

The study reported in this issue of the Journal by Jhun and colleagues (pp. 1322-1330) has, at one level, immediate patient management implications, but at another level, it raises fundamental questions about the relationship between MAC lung disease and underlying conditions such as bronchiectasis....

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Bibliographic Details
Published inAmerican journal of respiratory and critical care medicine Vol. 198; no. 10; pp. 1252 - 1253
Main Authors Griffith, David E, Aksamit, Timothy R
Format Journal Article
LanguageEnglish
Published United States American Thoracic Society 15.11.2018
Subjects
Antibiotics
Bacterial infections
Infections
Lung diseases
Microbiota
Patients
Success
Systematic review
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Summary:The study reported in this issue of the Journal by Jhun and colleagues (pp. 1322-1330) has, at one level, immediate patient management implications, but at another level, it raises fundamental questions about the relationship between MAC lung disease and underlying conditions such as bronchiectasis. [...]the authors again demonstrate the importance of apparent MAC reinfection during and after a course of ostensibly adequate MAC therapy (2, 6). [...]the authors found that few patients, just 3% of the original cohort and 22% of the culture positive persisters, developed macrolide-resistant MAC isolates. David E. Griffith, M.D. Pulmonary Infectious Disease Section University of Texas Health Science Center Tyler, Texas Timothy R. Aksamit, M.D. Pulmonary Diseases and Critical Care Medicine Mayo Clinic Rochester, Minnesota Originally Published in Press as DOI: 10.1164/rccm.201807-1243ED on August 9, 2018 References 1.Jhun BW, Kim S-Y, Moon SM, Jeon K, Kwon OJ, Huh HJ, et al.
Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Editorial-2
ObjectType-Commentary-1
ISSN:1073-449X
1535-4970
DOI:10.1164/rccm.201807-1243ED