Left ventricular performance improves late after aortic valve replacement in patients with aortic stenosis and reduced ejection fraction

• Published in: The American journal of cardiology Vol. 76; no. 8; pp. 612 - 615
• Main Authors: Robiolio, Paul A., Rigolin, Vera H., Hearne, Steven E., Baker, William A., Kisslo, Katherine B., Pierce, Cynthia H., Bashore, Thomas M., Harrison, J.Kevin
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 15.09.1995; Elsevier; Elsevier Limited
• Subjects: Aged; Aortic Valve; Aortic Valve Stenosis - diagnosis; Aortic Valve Stenosis - physiopathology; Aortic Valve Stenosis - surgery; Biological and medical sciences; Bioprosthesis; Cardiovascular disease; Female; Heart; Heart Valve Prosthesis; Humans; Male; Medical procedures; Medical sciences; Middle Aged; Postoperative Period; Prospective Studies; Stroke Volume; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the heart; Time Factors; Ventricular Function, Left; Human; Prognosis; Treatment; Cardiac valvular disease; Surgery; Cardiovascular disease; Narrowing; Left ventricle performance; Aortic valve; Ejection fraction
• ISSN: 0002-9149; 1879-1913
• DOI: 10.1016/S0002-9149(99)80168-4

EF in patients with aortic stenosis and reduced EF who underwent aortic valve replacement did not improve by 1 week postoperatively despite rectification of afterload mismatch. By 6 months, however, EF significantly improved without any further change in ventricular loading conditions. This implies that the benefit from aortic valve replacement (when measured by LV ejection performance) may not be evident until late postoperatively.