Biosensors and multiple mycotoxin analysis

An immunochemical biosensor assay for the detection of multiple mycotoxins in a sample is described. The inhibition assay is designed to measure four different mycotoxins in a single measurement, following extraction, sample clean-up and incubation with an appropriate cocktail of anti-mycotoxin anti...

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Bibliographic Details
Published inFood control Vol. 14; no. 4; pp. 251 - 254
Main Authors van der Gaag, Bram, Spath, Sabine, Dietrich, Heidi, Stigter, Edwin, Boonzaaijer, Gerben, van Osenbruggen, Ton, Koopal, Kees
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 01.06.2003
Subjects
analytical specificity
antibodies
biosensors
mycotoxins
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Summary:An immunochemical biosensor assay for the detection of multiple mycotoxins in a sample is described. The inhibition assay is designed to measure four different mycotoxins in a single measurement, following extraction, sample clean-up and incubation with an appropriate cocktail of anti-mycotoxin antibodies. The different mycotoxins could be detected simultaneously in relevant concentrations within a time frame of 25 minutes, including the time needed for sensor regeneration. The application of the developed assay on presently available miniature SPR devices allows the development for low-cost instruments, which can be used in field measurements.
Bibliography:http://dx.doi.org/10.1016/S0956-7135(03)00008-2
ISSN:0956-7135
1873-7129
DOI:10.1016/S0956-7135(03)00008-2