Very late stent thrombosis 5 years after IVUS-guided drug-eluting stent implantation

It is well accepted that drug-eluting stents (DES) are effective in reducing restenosis, although implantation of DES may result in increased occurrence of stent thrombosis. The study describes the case of a patient with very late stent thrombosis (VLST) despite intravascular ultrasound (IVUS) contr...

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Bibliographic Details
Published inBlood coagulation & fibrinolysis Vol. 23; no. 7; p. 666
Main Authors Sauter, Reinhard J, Steeg, Martin, Bocksch, Wolfgang, Schreieck, Jürgen, Gawaz, Meinrad, Langer, Harald F
Format Journal Article
LanguageEnglish
Published England 01.10.2012
Subjects
Aged
Coronary Angiography
Coronary Thrombosis - diagnostic imaging
Coronary Thrombosis - etiology
Drug-Eluting Stents - adverse effects
Female
Humans
Paclitaxel - administration & dosage
Risk Factors
Treatment Outcome
Ultrasonography
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Summary:It is well accepted that drug-eluting stents (DES) are effective in reducing restenosis, although implantation of DES may result in increased occurrence of stent thrombosis. The study describes the case of a patient with very late stent thrombosis (VLST) despite intravascular ultrasound (IVUS) control after implantation of a paclitaxel-eluting stent, an adequate response to antiplatelet therapy, and the lack of distinct risk factors for VLST. Stent thrombosis remains a serious complication after stent implantation even after prolonged time, and studies are urgently needed to optimize diagnosis and treatment of VLST.
ISSN:1473-5733
DOI:10.1097/MBC.0b013e3283563150