Expression of inflammasome complex mRNA and its targeted microRNA in type 2 diabetes mellitus: A possible predictor of the severity of diabetic nephropathy

Highlights Concomitant elevated expression of Caspase‐1 in respect of reduced eGFR among DN may serve as better explainable marker for the adverse prognosis of the disease Study may open new horizon to understand patho‐mechanism with the aid of Inflammasome‐complex.

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Bibliographic Details
Published inJournal of diabetes Vol. 11; no. 1; pp. 90 - 92
Main Authors Bhattacharjee, Chandra K., Paine, Suman K., Mahanta, Jagadish, Borphukan, Sawjib, Borah, Prasanta K.
Format Journal Article
LanguageEnglish
Published Melbourne Wiley Publishing Asia Pty Ltd 01.01.2019
John Wiley & Sons, Inc
Subjects
Biomarkers
Diabetes
Diabetic nephropathy
Hyperglycemia
inflammasome
Inflammation
microRNA
Nephrology
NLR family pyrin domain containing 3 (NLRP3)
Ribonucleic acid
RNA
hyperglycemia
microRNA
NLR family pyrin domain containing 3 (NLRP3)
inflammasome
diabetic nephropathy
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Summary:Highlights Concomitant elevated expression of Caspase‐1 in respect of reduced eGFR among DN may serve as better explainable marker for the adverse prognosis of the disease Study may open new horizon to understand patho‐mechanism with the aid of Inflammasome‐complex.
Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
ISSN:1753-0393
1753-0407
DOI:10.1111/1753-0407.12845