Enzymatic transformation of biologically active 1,3;1,6-beta-D-glucan. Structure and activity of resulting fragments

• Published in: Biochemistry (Moscow) Vol. 72; no. 1; pp. 29 - 36
• Main Authors: Elyakova, L A, Isakov, V V, Lapshina, L A, Nagorskaya, V P, Likhatskaya, G N, Zvyagintseva, T N, Reunov, A V
• Format: Journal Article
• Language: English
• Published: United States 01.01.2007
• Subjects: Animals; Antiviral Agents - chemistry; Glucan 1,3-beta-Glucosidase - metabolism; Glucans - chemistry; Glucans - metabolism; Hydrolysis; Magnetic Resonance Spectroscopy; Mollusca; Oligosaccharides - chemistry; Spisula - enzymology; Spisula sachalinensis; Structure-Activity Relationship; Substrate Specificity; Tobacco mosaic virus

The fragmentation of the biologically active 1,3;1,6-beta-D-glucan Antivir by endo-1,3-beta-D-glucanase LIV from crystalline styles of the marine mollusk Spisula sachalinensis was carried out. It was found that low molecular mass oligomers possessing a stabilizing effect on membranes and anti-viral...