Targeting the subthalamic nucleus

The small size and surrounding neuronal structures and fibre tracts make the STN a difficult stereotactic target. In this article we present the technique used by us to target the STN. Our combined experience from two centres comprises 18 lesions and 27 stimulator implants in the STN. Our criteria f...

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Bibliographic Details
Published inStereotactic and functional neurosurgery Vol. 77; no. 1-4; p. 87
Main Authors Aziz, T Z, Nandi, D, Parkin, S, Liu, X, Giladi, N, Bain, P, Gregory, R G, Joint, C, Scott, R B, Stein, J F
Format Journal Article
LanguageEnglish
Published Switzerland 01.01.2001
Subjects
Electric Stimulation Therapy - instrumentation
Electric Stimulation Therapy - methods
Electrocoagulation - instrumentation
Electrocoagulation - methods
Electrodes, Implanted
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging
Monitoring, Intraoperative
Parkinson Disease - surgery
Parkinson Disease - therapy
Recurrence
Retrospective Studies
Stereotaxic Techniques
Subthalamic Nucleus - physiopathology
Subthalamic Nucleus - surgery
Tomography, X-Ray Computed
Treatment Outcome
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Summary:The small size and surrounding neuronal structures and fibre tracts make the STN a difficult stereotactic target. In this article we present the technique used by us to target the STN. Our combined experience from two centres comprises 18 lesions and 27 stimulator implants in the STN. Our criteria for patient selection and the use of MRI, frame-on CT and volumetric image fusion are presented. The role of a movement disorder specialist neurologist in the operating theatre, local field potential recording, impedance monitoring, macrostimulation, post-operative CT/MRI and test stimulation are detailed.
ISSN:1011-6125
DOI:10.1159/000064602