Metal-organic framework composite Mn/Fe-MOF@Pd with peroxidase-like activities for sensitive colorimetric detection of hydroquinone

• Published in: Analytica chimica acta Vol. 1279; p. 341797
• Main Authors: Deng, Die, Wang, Ya, Wen, Shaohua, Kang, Yujie, Cui, Xiaoyan, Tang, Rong, Yang, Xiupei
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 23.10.2023
• Subjects: Colorimetric analysis; Hydroquinone; Metal-organic framework composite; Mimic enzyme; Hydroquinone; Metal-organic framework composite; Mimic enzyme; Colorimetric analysis
• ISSN: 0003-2670; 1873-4324
• DOI: 10.1016/j.aca.2023.341797

The construction of highly sensitive detection methods for hydroquinone (HQ) in environment and cosmetics is of great significance for environmental protection and human health. In this work, a novel detection method for HQ was successfully developed by constructing a metal-organic framework mimic enzyme colorimetric sensor (Mn/Fe-MOF@Pd1.0) with excellent peroxidase-like activity, which was synthesized by doping manganese ions into Fe-MOF by introducing bimetallic active centers, thereby improving the peroxidase-like activity of Fe-MOF, and the acid resistance and stability of Mn/Fe-MOF were improved by supporting palladium (Pd NPs). It is proven that Mn/Fe-MOF@Pd1.0 promoted the decomposition of hydrogen peroxide (H2O2) to generate active species, therefore, oxidized chromogenic substrate discoloration. On this basis, the detection of HQ based on the Mn/Fe-MOF@Pd1.0 colorimetric sensor was constructed, in which the limit of detection (LOD) was 0.09 μM in the linear range of 0.3–30 μM. Furthermore, Mn/Fe-MOF@Pd1.0 was successfully used for detecting HQ in hydroquinone whitening cream and actual water samples. The successful synthesis of Mn/Fe-MOF@Pd1.0 may provide new insights for further study of the enzyme-like activity of metal-organic framework composites, and the constructed facile and sensitive sensor system could broaden the application prospects of HQ detection. Schematic diagram of the synthesis of Mn/Fe-MOF@Pd and its colorimetric sensing of HQ [Display omitted] •A novel metal-organic framework composite Mn/Fe-MOF@Pd1.0 was successfully synthesized.•The peroxide-like activity of Fe-MOF was increased by constructing bimetallic active sites.•The acid tolerance and stability of Mn/Fe-MOF were improved by loading palladium (Pd).•The mechanism of the peroxidase-like catalyzed reaction of Mn/Fe-MOF@Pd1.0 was discussed.•The colorimetric sensor constructed by Mn/Fe-MOF@Pd1.0 has high selectivity and sensitivity to hydroquinone (HQ).