Diastolic (dys-)function and electrophysiology

Cross-talk between cardiac electrical and mechanical function is a bidirectional process: The origin and spread of electric excitation govern cardiac contraction and relaxation, while the mechanic environment provides feedback information to the heart's electric behavior. The latter tends to be...

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Bibliographic Details
Published inCardiology clinics Vol. 18; no. 3; p. 637
Main Authors Kohl, P, LeGuennec, J Y, White, E
Format Journal Article
LanguageEnglish
Published Netherlands 01.08.2000
Subjects
Animals
Arrhythmias, Cardiac - physiopathology
Arrhythmias, Cardiac - therapy
Diastole - physiology
Electric Countershock
Electrocardiography
Humans
Myocardial Contraction - physiology
Sinoatrial Node - physiopathology
Ventricular Dysfunction, Left - physiopathology
Ventricular Dysfunction, Left - therapy
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Summary:Cross-talk between cardiac electrical and mechanical function is a bidirectional process: The origin and spread of electric excitation govern cardiac contraction and relaxation, while the mechanic environment provides feedback information to the heart's electric behavior. The latter tends to be unduly disregarded by the medical community. This article reviews experimental findings on the effects of diastolic mechanics on cardiac electrophysiology, and describes physiological correlates, clinical manifestations, and therapeutic utility of cardiac mechanic stimulation in humans.
ISSN:0733-8651
DOI:10.1016/S0733-8651(05)70166-1