DNA aptamer selected for specific recognition of prostate cancer cells and clinical tissues

• Published in: Chinese chemical letters Vol. 28; no. 6; pp. 1252 - 1257
• Main Authors: Huang, Zhi-Xiang, Xie, Qin, Guo, Qiu-Ping, Wang, Ke-Min, Meng, Xiang-Xian, Yuan, Bao-Yin, Wan, Jun, Chen, Yuan-Yuan
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.06.2017
• Subjects: Aptamer; Cell-SELEX; Clinical tissues; PC–3M; Prostate cancer; Aptamer; Clinical tissues; PC–3M; Prostate cancer; Cell-SELEX

Prostate cancer is the most common malignancy in men lack of efficient early diagnosis and therapeutics,calling for effective molecular probes.Herein,we performed cell-based systematic evolution of ligands by exponential enrichment（cell-SELEX） to obtain specific recognition of human prostate cancer...