Identification of a Possible Somatic BRCA1 Mutation Affecting Translation Efficiency in an Early-Onset Sporadic Breast Cancer Patient

Papa et al report the description of a novel BRCA1 gene mutation potentially affecting BRCA1 gene expression in a woman with sporadic breast cancer who was a case subject in a population-based retrospective screening.

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Bibliographic Details
Published inJNCI : Journal of the National Cancer Institute Vol. 90; no. 13; pp. 1011 - 1012
Main Authors Papa, Sara, Seripa, Davide, Merla, Giuseppe, Gravina, Carolina, Fazio, Vito M., Giai, Maurizia, Sismondi, Piero, Serra, Anna, Saglio, Giuseppe, Rinaldi, Monica
Format Journal Article
LanguageEnglish
Published United States Oxford University Press 01.07.1998
Oxford Publishing Limited (England)
Subjects
Adult
Age of Onset
Bank reserves
Base Sequence
Breast Neoplasms - genetics
DNA, Neoplasm - chemistry
Female
Genes
Humans
Medical screening
Molecular Sequence Data
Mutation
Neoplasm Proteins - genetics
Sequence Analysis, DNA
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Summary:Papa et al report the description of a novel BRCA1 gene mutation potentially affecting BRCA1 gene expression in a woman with sporadic breast cancer who was a case subject in a population-based retrospective screening.
Bibliography:ark:/67375/HXZ-H3MJQTS4-6
Supported by Italian Ministero della Sanità RCIRCCS. We acknowledge IRCCS “Casa Sollievo della Sofferenza” and “Opera Padre Pio” for financial support and research fellowships (S. Papa, D. Seripa, and G. Merla).
istex:CF4E59CA3307EDE8BC4536B6C15F236D8522316F
SourceType-Scholarly Journals-1
ObjectType-Correspondence-2
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ISSN:0027-8874
1460-2105
DOI:10.1093/jnci/90.13.1011