Synthetic studies of quinolizidine 195C and derivatives

Sulfur-substituted dihydropyridones prepared by aza-Diels–Alder reactions were converted to the cis-2,6-disubstituted derivatives, which could then proceed through ring-closing metathesis (RCM) and cross metathesis (CM) reactions to give many quinolizidine derivatives, including two epimers of (±)-1...

Full description

Saved in:
Bibliographic Details
Published inTetrahedron Vol. 69; no. 5; pp. 1499 - 1508
Main Authors Chou, Shang-Shing P., Zhang, Jun-Wei, Chen, Kuan-Hua
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier Ltd 04.02.2013
Elsevier
Subjects
Chemistry
Chemistry, Organic
Cross metathesis
Decomposition reactions
Derivatives
Metathesis
Physical Sciences
Quinolizidine 195C
Quinolizidines
RCM
Ring-closing metathesis
Science & Technology
Tetrahedrons
Cross metathesis
Quinolizidine 195C
Ring-closing metathesis
Quinolizidines
CONCISE
CROSS-METATHESIS
DIELS-ALDER REACTIONS
OLEFIN METATHESIS
1-AZABICYCLIC ALKALOIDS
INDOLIZIDINE 167E
ARYLSULFONYL ISOCYANATES
THIO-SUBSTITUTED 1,3-DIENES
(+)-EPIQUINAMIDE
Online AccessGet full text

Cover

More Information
Summary:Sulfur-substituted dihydropyridones prepared by aza-Diels–Alder reactions were converted to the cis-2,6-disubstituted derivatives, which could then proceed through ring-closing metathesis (RCM) and cross metathesis (CM) reactions to give many quinolizidine derivatives, including two epimers of (±)-195C. [Display omitted]
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0040-4020
1464-5416
DOI:10.1016/j.tet.2012.12.017